EEC 2022 | The potential of the ketogenic diet for the treatment of drug-resistant epilepsy in children

Stefanie Prast-Nielsen, PhD, Karolinska Institute, Solna, Sweden, discusses the history of the ketogenic diet, and comments on a study investigating the gut microbiota and serum inflammation profile using machine learning algorithms and omics integration analysis. The findings of the study indicate that children with drug-resistant epilepsy (DRE) who had an anti-seizure response to the ketogenic diet had a different gut microbiota composition to those who did not have an anti-seizure response. Specifically, Dr Prast-Nielsen comments on the abundance of Bifidobacteria and its correlation to tumor necrosis factor alpha (TNF alpha) levels present in the serum. This interview took place at the 14th European Epilepsy Congress (EEC) 2022 in Geneva, Switzerland.