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MDS 2021 | Non-invasive spinal cord stimulation in Parkinson’s disease

Rubens Gisbert Cury, MD, University of São Paulo, São Paulo, Brazil discusses the possibility of using non-invasive stimulation of the spinal cord to improve symptoms in patients with Parkinson’s disease (PD). This idea was first tested in parkinsonian animal models as an invasive treatment, and has since been translated to humans, where improvements in gait have been demonstrated that have not yet been achieved by any available medications. Dr Cury describes new preliminary data on the use of non-invasive stimulation of the thoracic spinal cord which demonstrates that this approach, now being investigated in a Phase II clinical trial (NCT04783493), may be effective. This interview took place during the 2021 International Congress of Parkinson’s Disease and Movement Disorders.