Rigmor Jensen, MD, University of Copenhagen, Glostrup, Denmark, outlines the major unmet needs in the field of cluster headache. Firstly, increased awareness and education among clinicians and the general population is crucial to tackle the high rate of misdiagnosis currently seen. Prof. Jensen also highlights the need for new treatments that can abort a cluster bout and are well tolerated. This interview took place during the European Academy of Neurology 2021 congress.