Zaza Katsarava, MD, PhD, MSc, University of Essen, Essen, Germany, discusses preventive treatment outcomes beyond migraine/headache frequency and intensity. Prof. Katsarava highlights the importance of widening outcome measures to consider patient wellbeing, disease burden, and quality of life. Highly efficacious and well tolerated treatments are now available and continue to emerge and thus, treatment expectations are increasing above those of migraine non-specific agents. This interview took place during the European Academy of Neurology 2021 congress.