Joaquim Ferreira, MD, PhD, Faculty of Medicine, University of Lisbon, Lisbon, Portugal, discusses how the newly licensed COMT inhibitor opicapone has shown to have more benefits over the older treatment entacapone. Opicapone displays better motor performance by prolonging the ‘on-time’ in Parkinson’s disease patients. This interview was recorded during an online conference call with The Video Journal of Neurology (VJNeurology).