World Sleep 2022 | The TOPMed consortium in OSA research

Brain Cade, PhD, Brigham and Women’s Hospital, Boston, MA, expands on the role of the Trans-Omics for Precision Medicine (TOPMed) program, sponsored by the National Institutes of Health (NIH) National Heart, Lung and Blood Institute (NHLBI). The TOPMed program aims to provide disease treatments tailored to an individual’s unique genes and environment by integrating whole-genome sequencing (WGS) and other omics data with molecular, behavioral, imaging, environmental, and clinical data. TOPMed focuses on understanding the fundamental biological processes that underlie heart, lung, blood, and sleep (HLBS) disorders, including developing a multi-faceted approach to characterize obstructive sleep apnea (OSA). This interview was recorded at the World Sleep Congress 2022 in Rome, Italy.