AD/PD 2021 | APOE and TOMM40 as risk factors for Alzheimer’s disease

Marwan Sabbagh, MD, Lou Ruvo Center for Brain Health, Las Vegas, NV, discusses the contributions of Prof. Allen Roses, a pioneering neurologist, to Alzheimer’s disease research. Prof. Sabbagh highlights Prof. Roses’ most significant contributions, including discovering the link between APOE- Ɛ4 presence and risk of developing Alzheimer’s disease, which was controversial at the time. His second contribution to the field of Alzheimer’s disease research was suggesting that translocase of outer mitochondrial membrane 40 (TOMM40) could also affect the risk of developing Alzheimer’s disease. This interview took place during the AD/PD™ 2021 conference.