ISC 2023 | Natural history of pediatric large vessel occlusion stroke

Treatment standards have progressed drastically in adult ischemic stroke, with substantially more patients achieving good outcomes following the introduction of reperfusion therapy as the standard of care. However, a small sample size and lack of clinical equipoise has led to a paucity of comparative data in the pediatric stroke population and thus, progress has not kept up with the adult population. Kartik Bhatia, MBBS, PhD, Sydney Children’s Hospital Network, University of Sydney, Westmead, Australia, notes the findings of a population study on the natural history of pediatric ischemic stroke. Only one-third of patients with a large vessel occlusion (LVO) received mechanical thrombectomy, while the rest were treated conservatively. More than 65% of the LVO population experienced moderate-severe disability or death at 3 months. Up to date guidelines and comparative data are needed to increase the uptake of reperfusion therapy in pediatric stroke. This interview took place during the International Stroke Conference (ISC) 2023 in Dallas, TX.

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