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AAN 2022 | Rehabilitation combined with excitatory transcranial magnetic stimulation for patients with MS

Widespread exploratory use of neuromodulation has increased in recent years, in an attempt to reduce symptoms such as cognitive issues and fatigue for patients with multiple sclerosis (MS). Letizia Leocani, MD, PhD, Scientific Institute Vita-Salute University San Raffaele, Milan, Italy, discusses a recent study which investigated the effectiveness of using a H-coil to stimulate certain regions of the brain, in combination with rehabilitation therapies. Patients underwent this treatment for 3 weeks. The outcome which achieved the biggest response was resistance to fatigue while walking, with patients experiencing a more significant effect after 3 months of follow-up. Dr Leocani discusses the need for better monitoring to understand how and why patients are improving their motor skills after this treatment, as well as the need for further research into baseline predictors of response. The next steps for this area of research include a longer trial duration and closer monitoring of patients after the treatment has finished. This will hopefully help to provide information to patients about what to do after they have been discharged from intensive in-patient rehabilitations, in order to maintain their motor skills. This interview took place at the American Academy of Neurology 2022 Congress in Seattle, WA.