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AAN 2022 | Reforming the patient exclusion and inclusion criteria in clinical trials for stroke

Johanna Fifi, MD, FAAN, Icahn School of Medicine at Mount Sinai, New York, NY, comments on the selection criteria of the POSITIVE trial (NCT01852201) which assessed endovascular management in patients with stroke. Due to differences in selecting patients for treatment in clinical practice and trials, patients who may benefit might not be eligible in clinical trials. Dr Fifi subsequently highlights the need to educate clinicians and conduct trials that address these gaps in the selection criteria. This interview took place at the American Academy of Neurology 2022 Congress in Seattle, WA.