Angelo Labate, MD, Magna Graecia University of Catanzaro, Catanzaro, Italy, discusses the neurophysiology and neuroimaging of psychogenic non-epileptic seizures (PNES), including how video electroencephalograph (EEG) can be used to distinguish between epileptic seizures and PNES. In the neuroimaging field, Prof. Labate mentions that there is not much data regarding traditional imaging among patients with PNES. This interview took place at the European Academy of Neurology 2021 congress.