Jan Claassen, MD, PhD, Columbia University Medical Center, New York, NY, shares his perspectives on therapies for disorders of consciousness. Some options to treat these disorders include invasive procedures – for instance, the implantation of stimulators into the brain through surgery. Dr Claassen highlights the use of non-invasive approaches, such as focused ultrasound. This interview took place during the American Academy of Neurology (AAN) 2021 Annual Meeting.