MDS 2022 | Blood biomarkers and their association with non-motor symptoms in early Parkinson’s disease

Jaslovleen Kaur, MBBS, National Neuroscience Institute, Singapore, & Dayanand Medical College and Hospital, Ludhiana, India, discusses an ongoing study looking at blood biomarkers associated with non-motor symptoms in early Parkinson’s disease (PD). The longitudinal study compares various baseline blood biomarkers with the non-motor symptoms of the early PD cohort, using standard scales for multiple profiles, including sleep, depression, anxiety, fatigue, and apathy. Baseline data showed that total cholesterol and HDL were significantly associated with anxiety, and uric acid, apolipoprotein-B, triglycerides, and HDL were significantly associated with poor sleep quality. Future work should further explore and validate these biomarkers. This interview took place at the 2022 International Congress of Parkinson’s Disease and Movement Disorders in Madrid, Spain.

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