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ESOC 2022 | Investigating sex differences in clinical symptoms, pre-stroke disability, and hospital workflow

Mariam Ali, Medical Student, PhD Student, Leiden University Medical Center, Leiden, & Amsterdam University Medical Center, Amsterdam, The Netherlands, shares the findings of a study looking at sex differences in patients with anterior circulation large vessel occlusion. The analysis aimed to understand why women have worse outcomes after endovascular therapy. Over 4800 patients from the MR CLEAN registry who underwent endovascular treatment were included in the study, which assessed hospital workflow, pre-stroke disability, and clinical presentation. It was shown that women less often achieved good functional outcome at 90-days compared with men. While no differences were seen in hospital workflow, mean onset-to-door time was longer in women and women more often had pre-stroke disability. Highlighting these differences and investigating the underlying causes may help to improve treatment outcomes in women. This interview took place at European Stroke Organisation Conference 2022 in Lyon, France.