Raffaele Ornello, MD, University of L’Aquila, Avezzano, Italy, comments on the 2022 update of the European Headache Federation (EHF) guideline on the use of monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway for migraine prevention. Novel insights from randomized controlled clinical trials and real-world studies have improved the knowledge about those treatments. Thus, a guideline update was needed and included evidence-based recommendations on the patient population that will benefit the most from treatment with anti-CGRP antibodies, as well as suggestions regarding the long-term management of those treatments. This interview took place at the 16th European Headache Congress (EHC) in Vienna, Austria.
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