Michelle Canavan, MB, BCH, BAO, PhD, National University of Ireland, Galway, Ireland, describes the advances reported in the field of fluid-based and imaging biomarkers for the detection of vascular dementia as a key highlight from the AD/PD™ 2021 conference. She also discusses some of the major challenges facing the field of dementia research including the fact that dementia is rarely reported as a primary outcome in clinical trials. This interview took place during the AD/PD™ 2021 conference.