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ECTRIMS 2022 | Alterations of the salience/midcingulo-insular network across pathologies

Lucina Qazi Uddin, PhD, UCLA Brain Research Institute, Los Angeles, CA, outlines the implications of the salience/midcingulo-insular network for pathologies affecting brain connectivity. Initially, Dr Uddin’s research mainly focused on autism spectrum disorder: how insular dysfunction relates to the condition or if it could be used to differentiate children with the diagnosis from typically developing children. But because the salience/midcingulo-insular network is involved in such broad functions, it is likely affected across disorders, with various studies now investigating network alterations in schizophrenia, Alzheimer’s disease, and depression. This interview took place at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress 2022 in Amsterdam, The Netherlands.

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