The XXV World Congress of Neurology (WCN 2021) is taking place virtually 3-7th October 2021, jointly organized by the World Federation of Neurology (WFN) and the Society of Italian Neurology (SIN). Congress President, Antonio Federico, MD, PhD, University of Siena, Siena, Italy, shares what participants can expect from this year’s meeting, highlighting key reasons to get involved. The online platform will host over 100 scientific and teaching sessions for more than 4000 participants registered from across the world. This interview took place during the XXV World Congress of Neurology.