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AHS 2022 | Future directions and challenges concerning pain modulation in post-traumatic headaches

Vimala Bharadwaj, PhD, Stanford University School of Medicine, Stanford, CA, discusses the challenges concerning oxytocin administration and the future study directions in pain modulation of post-traumatic headache. One of the primary challenges faced is the administration of oxytocin; in the rodent model, the injection goes lower than a SC injection, thus, much consideration is required to limit pain when moving forward in humans. With the site of injection being very accessible, there is great potential in utilizing this procedure for humans. The implications would be immense; by treating patients with traumatic brain injury as early as possible, the persistence of headaches and pain could be drastically reduced. This interview took place during the 2022 American Headache Society (AHS) Meeting in Denver, CO.