ESOC 2022 | Highlights in stroke: pollution exposure, tenecteplase, and tranexamic acid

Thorsten Steiner, MD, PhD, Frankfurt Höchst Clinic, Frankfurt & Heidelberg University, Heidelberg, Germany, shares insights into the key data presented at the European Stroke Organisation Conference 2022. A large study of over 80,000 patients analyzed the impact of particulate matter exposure on hemorrhagic stroke risk. Long-term exposure to black carbon and dust was shown to significantly increase risk of hemorrhagic stroke hospitalization (1 mcg/m^3 increase led to a 46.3% and 25.7% increase in hemorrhagic stroke risk for black carbon and dust, respectively). Prof. Steiner also highlights the TICH-NOAC trial (NCT02866838), which enrolled 63 patients with novel direct oral anticoagulant-associated intracerebral hemorrhage (NOAC-ICH) to receive tranexamic acid or placebo. No evidence was found to show that tranexamic acid prevented hematoma expansion, but it appeared safe. This interview took place at European Stroke Organisation Conference 2022 in Lyon, France.