VJNeurology is committed to improving our service to you

Share this video  

VJNeurology is committed to improving our service to you

MS at the Limits 2022 | Future of genetics in MS: understanding disease progression

Sergio Baranzini, PhD, The University of California San Francisco, San Francisco, CA, clarifies that the next frontier in multiple sclerosis (MS) genetics is to determine whether progression has a genetic basis. The International MS Genetics Consortium has endeavored to answer this question and has recently conducted the largest genome-wide association study utilizing MS progression as the outcome. In this study, all patients have MS, but they have varying levels of progressive disability; therefore, the aim was to determine whether genetic risk factors play a role in the differences in progression in individuals. The results from the study suggest that MS progression is at least partly genetically determined since the phenotype is heritable. Thus, the next step is to determine where in the genome the heritability signal is coming from. This interview took place during the 2022 Multiple Sclerosis at the Limits Conference in London, UK.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.