Treatments capable of remyelination are a significant unmet need for patients with multiple sclerosis (MS). Christian Cordano, MD, PhD, UCSF Weill Institute for Neurosciences, San Francisco, CA, discusses the visual pathway as a measure to study remyelination. A study on patients with relapsing MS and chronic demyelinating optic neuropathy receiving clemastine showed that patients experienced a reduction in latency delay on full-field visual-evoked potentials while on the antihistamine treatment, demonstrating that the drug has a possible remyelinating effect and highlighting the value of ophthalmology in treating MS. This interview took place at the American Academy of Neurology 2022 Congress in Seattle, WA.