Afagh Garjani, MD, Nottingham University Hospitals NHS Trust, Nottingham, UK, talks on the need for population-based studies to determine the true extent of the effects of SARS-CoV-2 infection on patients with multiple sclerosis (MS). Investigations need to assess both clinician-reported COVID-19 cases of hospitalized patients and self-reported cases from patients with MS living in the community. This interview took place during the American Academy of Neurology (AAN) 2021 Annual Meeting.