Tanuja Chitnis, MD, Brigham and Women’s Hospital, Boston, MA, discusses the current cognitive assessment strategies used in multiple sclerosis (MS) and how these approaches are changing. Typical assessments in routine use include questionnaires for patients to note their own changes or formal neuropsychological tests, such as the Rao Brief Repeatable Neuropsychological Battery (BRNB). Over time, batteries have become briefer, including few highly informative tests like the single-digit modality test. Dr Chitnis also comments on the recent rise in telemedicine and how translating MS assessments to fit this approach is of growing importance. This interview took place during the ACTRIMS Forum 2021.