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EAN 2022 | Blood-based biomarkers are one of the greatest developments in neuroimmunology

Neuroimmunology is a rapidly progressing field, with studies of basic science, disease models, and neurological immune therapy driving key developments in our understanding of not only neuroimmunological disease, but also the immune/inflammatory mechanisms underlying neurological and psychiatric disease manifestations. Stefan Bittner, MD, Johannes Gutenberg-University, Mainz, Germany, discusses the development of novel blood-based biomarkers as the hottest topic in clinical neuroimmunology. Neurofilament light (NfL) is a measure of neuronal damage and has been widely shown to provide valuable information in several neurological diseases, notably multiple sclerosis. Prof. Bittner highlights NfL as a putative first-in-class liquid biomarker on its way into clinical practice. This interview took place at the European Academy of Neurology (EAN) 2022 Congress in Vienna, Austria.

Disclosures

Prof. Bittner received honoria and compensation for travel expenses from Biogen, Bristol Myers Squibb, Novartis, Merck Serono, Roche, Sanofi Genzyme and TEVA. His research is funded by Deutsche Forschungsgemeinschaft (DFG), Hertie Foundation and Hermann- and Lilly-Schilling Foundation.