Gavin Giovannoni, MBBCh, PhD, FCP, FRCP, FRCPath, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK, discusses the benefits of using therapies that do not have a strong scientific basis for treating multiple sclerosis (MS). Most of the treatments for MS are repurposed from cancer or other autoimmune diseases. Without individual investigation, a scientific case cannot be made. Prof. Giovannoni mentions that innovations in therapies start from treatments that do not have a strong scientific basis and in order to transition to a regulatory phase, treatments must be investigated in a pre-regulatory phase. This interview took place during the Virtual World Congress on Controversies in Neurology (CONy) 2020.