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MS Frontiers 2022 | Early diagnosis and treatment for multiple sclerosis prevention

A wealth of new evidence has created a paradigm shift in the treatment of multiple sclerosis (MS) in recent years, with clinicians now prioritizing early and aggressive treatment of their patients. As our understanding of radiologically isolated syndrome (RIS) and the MS prodrome grows, questions are arising regarding the feasibility of disease prevention. Klaus Schmierer, MB BS, PhD, FRCP, Queen Mary University of London & The Royal London Hospital of Barts Health NHS Trust, London, UK, talks on prevention trials and how cohorts can be enriched for high-risk individuals based on Epstein-Barr virus (EBV) antibody status, genetic predisposition, and HLA subtype. One key interest is looking to push diagnosis further into ‘pre-diagnostic’ phases. This interview took place at the MS Frontiers 2022 congress in Swansea, UK.

Disclosures

KS has received research support from Biogen, the healthcare business of Merck KGaA (Darmstadt, Germany), and Novartis; speaking honoraria from, and/or served in an advisory role for, Amgen- Gensenta, Biogen, EMD Serono, the healthcare business of Merck KGaA (Darmstadt, Germany), Novartis, Roche, Sanofi, and Teva; and remuneration for teaching activities from AcadeMe, Medscape, and the Neurology Academy.