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IHC 2021 | Phenome-wide analysis and causal relationships between migraine and other complex traits

Luis Marco García-Marín, Biotechnology Engineer, PhD student in Statistical Genetics, QIMR Berghofer Medical Research Institute & The University of Queensland, Brisbane, Australia, talks on the results from analysis of the causal relationship between migraine and other complex traits. The study compared migraine data with 1504 complex traits to estimate their genetic relations and assess the potential association. The results suggested that hypertension and blood clot formation were causally associated with an increased migraine risk, indicating that there is a potential vascular component to migraine and that other factors such as stress and work environment also contributed to this. Mr García-Marín highlights the importance of incorporating multiple study designs to get the best outcomes. This interview took place during the International Headache Congress 2021.