Liborio Parrino, PhD, Università degli Studi di Parma, Parma, Italy, talks on the under investigated topic of sleep as a link between the brain and the gut. Prof. Parrino highlights cases of periodic myoclonus due to a lack of iron, exemplifying the impact that diet can have on sleep. Much remains to be discovered about the complex, multifaceted connection between sleep and nutrition. This interview took place at the European College of Neuropsychopharmacology congress 2021.