Bernhard Steinhoff, MD, PhD, Kork Epilepsy Center, Kehl-Kork, Germany, discusses the burden of epilepsy in different age groups. Epilepsy can develop at any age and affects people of all ages. Disease burden is, therefore, dependent on what life stage epilepsy starts. When epilepsy develops in early childhood, there is a long-life burden that neurologists and pediatricians need to consider. If epilepsy starts during adolescence, the social implications of the disease are an essential concern. Finally, it is crucial to consider drug-drug interactions in elderly patients, many of whom will likely present comorbidities. This interview took place at the 2022 Congress of the European Academy of Neurology (EAN) in Vienna, Austria.