MDS 2022 | Innate and adaptive immunity in Parkinson’s disease

Marina Romero-Ramos, PhD, Aarhus University, Aarhus, Denmark, gives an overview of the work carried out by her team investigating the role of the innate immune cells in Parkinson’s disease. While initial studies mainly looked at microglia, the group also focused on peripheral immune cells, including monocytes, macrophages, and T-cells. Their work has gathered evidence that immunity is associated with Parkinson’s disease and that the immune response observed involves a coordinated response between the brain and the periphery. Additionally, the immune changes reported are stage-specific and are associated with neuronal events. This interview took place at the 2022 International Congress of Parkinson’s Disease and Movement Disorders in Madrid, Spain.

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