Jessica Ailani, MD, FAAN, Medstar Georgetown University Hospital, Washington, DC, outlines the details of the ‘Acute therapies for migraine’ industry therapeutic update session at AAN 2021. The session focuses on dihydroergotamine use, and the benefits of non-oral medications for patients with migraine. Data from the Phase III STOP 301 study (NCT03557333) of INP104 for the acute treatment of migraine will be presented. INP104, dihydroergotamine mesylate, uses a novel ‘precision olfactory delivery’ (POD) system to target the vascular-rich upper nasal cavity. This interview took place during the American Academy of Neurology (AAN) 2021 Annual Meeting.