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EAN 2022 | Cognitive relapses as markers of disease progression in MS

Celia Oreja-Guevara, MD, PhD, University Hospital San Carlos, Madrid, Spain, talks on the use of cognitive relapses as markers of disease progression in multiple sclerosis (MS). As well as being affected during typical MS relapses, isolated cognitive relapses can occur in the absence of new sensorimotor symptoms. Studies have shown that these cognition changes are not associated with fatigue or depression and have been associated with long-term cognitive decline. Dr Oreja-Guevara notes that cognitive relapses should be viewed as relevant reflections of disease activity and highlights cognitive performance as a potential predictive marker in MS. This interview took place at the European Academy of Neurology (EAN) 2022 Congress in Vienna, Austria.