Jennifer Graves, MD, PhD, MAS, University of California San Diego School of Medicine, San Diego, CA, outlines the findings of studies investigating biological age factors in multiple sclerosis (MS). Age has been epidemiologically identified as one of the strongest risk factors for more rapid disability progression. To understand the factors behind the relationship between age and disability in MS, leukocyte telomere length and anti-müllerian hormone levels (in women) were investigated as markers of biological aging. The results showed that both markers were associated with the development of disability and brain atrophy in patients with MS. This interview took place during the ACTRIMS Forum 2021.