Steven Galetta, MD, FAAN, NYU Langone Medical Center, New York, NY, discusses the post hoc analysis of RENEW (NCT01721161) and RENEWED (NCT02657915), determining whether structural/functional changes in the retina may predict long-term visual outcomes in multiple sclerosis (MS). Dr Galetta emphasizes that structural changes correlate with functional changes, meaning that when patients have a functional disability, they tend to have structural abnormalities. Finally, Dr Galetta gives examples of tests to unravel these structure-function correlations and highlights the possible translation to therapeutic approaches. This interview took place during the American Academy of Neurology (AAN) 2021 Annual Meeting.
Dr Galetta has been a consultant for Biogen and Genentech in the past.