ESOC 2022 | Impact of stroke etiology on clot composition

Rosanna Rossi, PhD, National University of Ireland Galway, Galway, Ireland, discusses acute ischemic stroke clot characteristics and how they associate with clinical and pathophysiological factors. Several studies have assessed the histopathologic features of thrombi removed during endovascular therapy, investigating them in the context of clinical information. Dr Rossi and colleagues have shown that large artery atherosclerotic (LAA) clots are typically larger and significantly more red blood cell rich. Whereas cardioembolic clots are smaller and have higher fibrin and platelet content than LAA clots. Through analysis of clot characteristics and proteomics, it is hoped that novel biomarkers for stroke etiology may be identified. This interview took place at the ESOC 2022 congress in Lyon, France.