EAN 2022 | The human functional connectome in neurological diseases

The imaging field has shifted from using techniques to look at specific brain regions to new tools showing how different brain areas connect and communicate. Massimo Filippi, MD, Vita-Salute San Raffaele University, Milan, Italy, explains how network-based analyses of functional connections have provided a new strategy to study the brain of patients with neurological disorders. These assessments can provide better phenotyping of neurological conditions and improve the understanding of the clinical manifestations noted in those patients. Network-based analyses also enable the identification of different stages of the diseases and connectivity profiles associated with different clinical outcomes and provide the opportunity to understand how pathological changes propagate throughout the disease course. This interview took place at the 2022 Congress of the European Academy of Neurology (EAN) in Vienna, Austria.