ECTRIMS 2021 | Higher repair capability in early-onset vs late-onset pediatric multiple sclerosis

Early-onset pediatric multiple sclerosis (MS) is rare, occurring in only 0.2-0.6% of all MS cases. In this video, Ermelinda De Meo, MD, University Vita-Salute San Raffaele, Milan, Italy, describes the results from a study exploring the disease course and prognosis of early-onset pediatric MS (disease onset before age 11) vs late-onset pediatric MS (disease onset after age 11). Overall, results indicated a better prognosis for early-onset patients, which suggests immune and adaptive brain responses are different from late-onset patients, with a higher repair capability and brain plasticity. This interview took place at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) congress 2021.