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Improving ALS management: diagnosis and treatment

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with highly variable clinical features and prognosis, making the diagnosis challenging. And despite years of research, there is currently no treatment that cures patients with ALS. Instead, the basis of ALS disease management is focused on timely intervention to effectively manage symptoms, optimize function, and help ensure the quality of life. Recent developments in ALS research have fueled progress in the field and are shaping research trajectories.

In this podcast, Matthew Kiernan, MBBS, PhD, DSc, FRACP, FAHMS, University of Sydney, Sydney, Australia; and Nigel Leigh, MBBS, PhD, FRCP, FAAN, FMedSci, University of Sussex, Brighton, UK, discuss crucial developments in our understanding of the underlying mechanisms of ALS, strategies to improve diagnosis and outline the pipeline of late-stage therapeutic options for patients with ALS.

Date: 9th September 2022